Juan Manuel Marquez has been in four wars with Manny Pacquiao, so he knows better than anyone what the Filipino fight icon is capable of inside the ring.
The proud Mexican champion has also fought against Floyd Mayweather, giving Marquez a unique perspective about the upcoming mega-fight on May 2 in Las Vegas.
And unlike most observers, Marquez sees Mayweather struggling with Pacquiao.
"Floyd Mayweather isn’t really used to fighting with southpaws," Marquez said on the Mexican show Golpe Y Golpe.
Marquez detailed how Pacquiao can break through Mayweather's vaunted defense.
"We know how Floyd Mayweather uses his shoulder roll, so with an orthodox fighter he can dodge many of those shots and wait for openings in his opponents than counter. Manny Pacquiao on his part has to use his speed, and lateral movement and in turn do not give Mayweather any space or minimal space to make him uncomfortable on that very stance," said Marquez.
The Mexico City native also took note what punches Pacquiao could use to bother Mayweather.
"The right hook will be key as a lefty for Manny Pacquiao. can set it up by using a left jab to the body and following it up with a hook from the outside and repeating a double hook and he can finish it off with a straight left. The repetition will be key in landing those combinations and Pacquiao has to change it up for Floyd not to adapt," said Marquez, adding that Mayweather's boxing IQ makes the brash American formidable.
"He sets traps and throws nice uppercuts from long distance, and he will use that reach advantage to do so. He will follow that up with counter rights and straight lefts from range because of that advantage."